Tracheobronchomalacia in newborns, which manifests with dynamic airway collapse and respiratory insufficiency, is difficult to treat.1,2 In an infant with tracheobronchomalacia, we implanted a customized, bioresorbable tracheal splint, created with a computer-aided design based on a computed tomographic image of the patient’s airway and fabricated with the use of laser-based three-dimensional printing, to treat this life-threatening condition.
At birth at 35 weeks’ gestation, the patient did not have respiratory distress and otherwise appeared to be in normal health. At 6 weeks of age, he had chest-wall retractions and difficulty feeding. By 2 months of age, his symptoms progressed and he required endotracheal intubation to sustain ventilation. The workup revealed the following: an anomalous origin and malposition of the pulmonary arteries, with crisscross anatomy; right pulmonary-artery hypoplasia; compression of the left mainstem bronchus between an abnormally leftward-coursing ascending aorta and an anteriorly displaced descending aorta; air trapping; and postobstructive pneumonia. Despite placement of a tracheostomy tube, mechanical ventilation, and sedation, ventilation that was sufficient to prevent recurring cardiopulmonary arrests could not be maintained.
We reasoned that the localized tracheobronchomalacia was the cause of this physiological abnormality and made a custom-designed and custom-fabricated resorbable airway splint. Our bellowed topology design, similar to the hose of a vacuum cleaner, provides resistance against collapse while simultaneously allowing flexion, extension, and expansion with growth. The splint was manufactured from polycaprolactone with the use of a three-dimensional printer.
Stop breadboarding and soldering – start making immediately! Adafruit’s Circuit Playground is jam-packed with LEDs, sensors, buttons, alligator clip pads and more. Build projects with Circuit Playground in a few minutes with the drag-and-drop MakeCode programming site, learn computer science using the CS Discoveries class on code.org, jump into CircuitPython to learn Python and hardware together, TinyGO, or even use the Arduino IDE. Circuit Playground Express is the newest and best Circuit Playground board, with support for CircuitPython, MakeCode, and Arduino. It has a powerful processor, 10 NeoPixels, mini speaker, InfraRed receive and transmit, two buttons, a switch, 14 alligator clip pads, and lots of sensors: capacitive touch, IR proximity, temperature, light, motion and sound. A whole wide world of electronics and coding is waiting for you, and it fits in the palm of your hand.
Have an amazing project to share? The Electronics Show and Tell is every Wednesday at 7:30pm ET! To join, head over to YouTube and check out the show’s live chat – we’ll post the link there.
Join us every Wednesday night at 8pm ET for Ask an Engineer!
Maker Business — Re-evaluating Amazon after its acquisition of Whole Foods
Wearables — It’s not a deal breaker
Electronics — Higher isn’t always better
Biohacking — Vitamin-C + Gelatin for Accelerated Recovery
Python for Microcontrollers — Supercharged Supercon with CircuitPython, Quoth the Raven MOAR PYTHON! #Python #Adafruit #CircuitPython #PythonHardware @circuitpython @micropython @ThePSF @Adafruit
Adafruit IoT Monthly — The S in IoT is for Security, Amazon announces Sidewalk and more!
Microsoft MakeCode — Xenomorph candy bucket and spooky workshops with MakeCode!
No comments yet.
Sorry, the comment form is closed at this time.