Gelatin Bio-Ink Could Lead to 3D Printed Organs

HumanTissue 3

Gelatin Bio-Ink Could Lead to 3D Printed Organs, ENGINEERING.com:

Surveys conducted by the German Organ Transplantation Foundation (DSO) say the number of organ transplant donors has plummeted 18 percent in the past year. With the demand for organ transplants increasingly overtaking supply, physicians are hopeful that new technologies (such as 3D printing) could one day fill in these gaps.

As a first big step, researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology (IGB) in Stuttgart recently announced that they’ve created a bio-ink suitable for printing a number of tissue types.

The key to the new ink’s versatility is its gelatin base. Gelatin, a derivative of collagen, is one of the main constituents of human tissues. While gelatin is normally in a gelatinous state at room temperature, the IGB researchers have created a way to keep the material in a liquid form. This makes it easier for the 3D printer to manipulate the material, depositing it onto a sterile sheet where it can then be cured with a UV light and rendered solid.

According to the IGB, “researchers can control the chemical modification of the biological molecules so that the resulting gels have differing strengths and swelling characteristics. The properties of natural tissue can therefore be imitated – from solid cartilage to soft adipose tissue.”

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