Once installed, configure your router to have DHCP clients use the Pi as their DNS server and then any device that connects to your network will have ads blocked without any further configuration. Alternatively, you can manually set each device to use the Raspberry Pi as its DNS server.
Each Friday is PiDay here at Adafruit! Be sure to check out our posts, tutorials and new Raspberry Pi related products. Adafruit has the largest and best selection of Raspberry Pi accessories and all the code & tutorials to get you up and running in no time!