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June 10, 2017 AT 2:00 am

Why Do Onions Make Us Cry?

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Via Discover

We all know that feeling: the burning sensation as we slice into a fresh onion, eyes watering and wincing to relieve the stinging. There are claims that home remedies can solve this problem, including burning a candle, putting the onion in the freezer before chopping, or cutting the onion underwater. In this article we will investigate the culprit behind our onion tears and a possible scientific resolution that has emerged in the 21st century.

The teary-eyed response to cutting an onion is due to the chemical syn-propanethial-S-oxide, which the onion has evolved as a defense mechanism against predators. Each cell inside the onion contains a vacuole filled with enzymes [1] called allinases that convert amino acid sulfoxides that are present in the onion cell to sulfenic acids [2] (namely 1-propenyl-L-cysteine sulphoxide, or PRENSCO)[3]; these are then transformed by another enzyme into syn-propanethial-S-oxide [4] (Fig 1).When the onion cell structure is broken during chopping, the enzymes are released and are then able to interact with other chemicals inside the onion cell, thus catalyzing the chemical reactions that produce syn-propanethial-S-oxide [1] (Fig 1).

The strong, spicy odor that onions emit when chopped are surprisingly not the culprit chemical that makes your eyes water. This odor is formed by the condensation of syn-propanethial-S-oxide to form odorous thiosulfanates [2]. Because syn-propanethial-S-oxide is a volatile sulfur compound, it easily diffuses into the air [1]. Your cornea contains nerves that relay information to the larger nerves responsible for touch, temperature, and pain detection on your face [2]. The nerves on your cornea detect the presence of syn-propanethial-S-oxide and send the signal to your central nervous system (Fig 2), which then stimulate the autonomic nerve fibers on the lachrymal glands to produce tears [2] in order to dilute the syn-propanethial-S-oxide. This is why referred to as lachrymatory compound or lachrymator, which can be defined as “an irritant that causes the eyes to fill with tears without damaging them” [5].

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