Nor are they particularly well-suited for delivering drug doses over an extended period of time. That’s where the somewhat squirm-inducing new treatment comes into play. It involves an eye patch studded with tiny dissolvable needles. The patch is placed onto the patient’s eye and then removed, leaving the microneedles embedded in their cornea. The microneedles consist of two layers: An outer layer which delivers an initial drug dose and an inner layer which delivers a secondary drug dose over the course of several days.
“This work provides a new strategy for efficient drug delivery into the eye,” Chen Peng, a professor in the School of Chemical and Biomedical Engineering at Nanyang Technological University, told Digital Trends. “With simple pressing of the eye patch on the eye, the detachable tiny needles can penetrate the ocular surface tissue, and serve as implanted micro-drug-reservoirs. The biphasic drug release kinetics enabled by the double-layered micro-reservoirs largely enhances the therapeutic efficacy.”
So far, the needle-studded eye patch has been tested on mice, where it demonstrated significantly more efficiency than regular eye drops.
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