Art Inspired by Cells from Aime Esslinger #ArtTuesday

(Jagged and Theft (2021) by Amie Esslinger)

Amie Esslinger finds inspiration in cellular biology. Jagged and Theft, specificallly references the JAG1 protein. Here’re more from Art the Science:

I came across JAG1 when looking into the mechanics of tumor growth and spread. It’s one of the pivotal players in an integral system that allows cells to latch onto one another to form tissue. It gets its name because its structure is a jagged form and when aided by other functions it will connect to its counterpart which has an inverted delta structure and is the receptor component. I imagine it’s like a key and lock connection, eventually locking together cells one by one. But apparently, when JAG1 is overexpressed in certain types of tissue, it can aid in the migration of an established cancer. As every JAG1 is compelled to connect to the coordinating receptor, it eventually will be responsible for sourcing local blood supply to nurse along the cancer as it migrates. *Apologies to any scientists, researchers, or oncologists for my possibly poor description of JAG1.

JAG1 protein stuck with me because it immediately conjured a visual structure. Then I imagined the theft of blood, health, and time. The painting and its title seemed to unfold.

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