Sequencing your DNA with a USB dongle and open source code #DNA #OpenSource @stackoverflow

Remember the scene from the Matrix where Neo unlocks his full power, and the world around him is revealed as lines of code running in all directions? What if you could see the world around you in this way?

Recent breakthroughs in nanopore sequencing, driven by developments in open-source software, have made it possible to greatly reduce the time it takes to decode a genome, shrinking what used to be a 15-day process to three days or less. It wasn’t so long ago that decoding a genome took years! To understand the code behind these new techniques, which have been dubbed UNCALLED, we chatted with Prof. Michael Schatz, the Bloomberg Distinguished Associate Professor of Computer Science and Biology at Johns Hopkins.

Imagine a hole so tiny that a single strand of DNA can fit through at a time. Push your genetic material through this pore, and the As, Ts, Gs, and Cs that make up a human genome will be revealed in sequence. So, how do you tell the four building blocks of DNA apart?

“It takes the most exquisite measurements you can imagine, measuring the changes in current associated with different bits of DNA,” he explains. “This is happening at the level of pico-amps—one-trillionth of an amp measurement—and we can get these readings in real time.” Five years ago, the equipment needed for this work would have been restricted to serious research facilities. Today, for about a thousand dollars, you can purchase a nanopore sequencer as a peripheral that connects to any computer via USB.

The current climate is far healthier and happier for academics like Schatz, who plans to continue open sourcing the software being created by his lab. “There’s just so much benefit from being able to share code and work collaboratively.

Read more on the StackOverflow Blog

As 2022 starts, let’s take some time to share our goals for CircuitPython in 2022. Just like past years (full summary 2019, 2020, and 2021), we’d like everyone in the CircuitPython community to contribute by posting their thoughts to some public place on the Internet. Here are a few ways to post: a video on YouTub, a post on the CircuitPython forum, a blog post on your site, a series of Tweets, a Gist on GitHub. We want to hear from you. When you post, please add #CircuitPython2022 and email to let us know about your post so we can blog it up here.

Stop breadboarding and soldering – start making immediately! Adafruit’s Circuit Playground is jam-packed with LEDs, sensors, buttons, alligator clip pads and more. Build projects with Circuit Playground in a few minutes with the drag-and-drop MakeCode programming site, learn computer science using the CS Discoveries class on, jump into CircuitPython to learn Python and hardware together, TinyGO, or even use the Arduino IDE. Circuit Playground Express is the newest and best Circuit Playground board, with support for CircuitPython, MakeCode, and Arduino. It has a powerful processor, 10 NeoPixels, mini speaker, InfraRed receive and transmit, two buttons, a switch, 14 alligator clip pads, and lots of sensors: capacitive touch, IR proximity, temperature, light, motion and sound. A whole wide world of electronics and coding is waiting for you, and it fits in the palm of your hand.

Join 32,000+ makers on Adafruit’s Discord channels and be part of the community!

Have an amazing project to share? The Electronics Show and Tell is every Wednesday at 7pm ET! To join, head over to YouTube and check out the show’s live chat – we’ll post the link there.

Join us every Wednesday night at 8pm ET for Ask an Engineer!

Follow Adafruit on Instagram for top secret new products, behinds the scenes and more

CircuitPython – The easiest way to program microcontrollers –

Maker Business — Pololu’s account of the chip shortage

Wearables — Monster-inspired costuming!

Electronics — How to make your own magnetic field probe!

Python for Microcontrollers — Python on Microcontrollers Newsletter: Raspberry Pi Pico turns one and more! #Python #CircuitPython @micropython @ThePSF

Adafruit IoT Monthly — 2021 in Recap!

Microsoft MakeCode — MakeCode Thank You!

EYE on NPI — Maxim’s Himalaya uSLIC Step-Down Power Module #EyeOnNPI @maximintegrated @digikey

New Products – Adafruit Industries – Makers, hackers, artists, designers and engineers! — JP’s Product Pick of the Week — 4pm Eastern TODAY! 1/25/22 @adafruit @johnedgarpark #adafruit #newproductpick

Get the only spam-free daily newsletter about wearables, running a "maker business", electronic tips and more! Subscribe at !

No Comments

No comments yet.

Sorry, the comment form is closed at this time.