See How Scientists Put Together the Complete Human Genome
Earlier this year researchers completed sequencing the human genome. Like any code, the last 8% took the longest to crack. Interesting chart on Scientific American showing the work and progress over the decades:
The human genome is at last complete. Researchers have been working for decades toward this goal, and the Human Genome Project claimed victory in 2001, when it had read almost all of a person’s DNA. But the stubborn remaining 8 percent of the genome took another two decades to decipher. These final sections were highly repetitive and highly variable among individuals, making them the hardest parts to sequence. Yet they revealed hundreds of new genes, including genes involved in immune responses and those responsible for humans developing larger brains than our primate ancestors. “Now that we have one complete reference, we can understand human variation and how we changed with respect to our closest related species on the planet,” says geneticist Evan Eichler of the University of Washington, one of the co-chairs of the Telomere-to-Telomere consortium that finished the genome.
some more info a on what a gapless genome means from the UC Santa Cruz:
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